Neuron-specific enolase by IHC

Alphabetical Test listing

Neuron-specific enolase by IHC-12376 - Technical only, 12379 - Technical & Interpretation

  
Neuron-specific enolase by IHC
  
12376 - Technical only, 12379 - Technical & Interpretation
  
LAB12376
LAB12379
  
NSE
  
  • All IHC stains will include a positive control tissue
  
  • May be useful in a panel for neuroendocrine tumors
  • Other more specific neuroendocrine markers include chromogranin, Synaptophysin, and Leu-7
  • Infrequent positive staining in many non-neuroendocrine tumors has been identified with NSE due to cross-reactivity
  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue block

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • NSE is an isoenzyme of the glycolytic enzyme enolase that is expressed primarily in neurons and neuroendocrine tissues
  • NSE is also expressed in platelets, T-lymphocytes, megakaryocytes, striated and smooth muscle cells

Staining pattern

  • Diffuse cytoplasmic

  
88342 - 1st stain
88341 - each additional stain
  
07/18/2017
  
10/19/2018