Neisseria gonorrhoeae (GC) is a common sexually transmitted infection and may be asymptomatic. N. gonorrhoeae primarily causes a lower genital tract infection, but if untreated, may cause disseminated disease or pelvic inflammatory disease with endometritis, salpingitis, pelvic peritonitis, and tubo-ovarian abscesses.
This test should be ordered in patients with symptoms of cervicitis or urethritis, as well as for screening asymptomatic patients.
Male urethral swab specimens:
Patient should not have urinated for at least 1 hour prior to specimen collection.
Male and female urine specimens:
Female endocervical or male urethral sample collections
Aptima Multitest swab transport media
Oral/mouth, rectal or vaginal sample collections
If patient has had a hysterectomy, collect vaginal or urine.
Endocervical specimens:
Use Aptima Unisex Swab Specimen Collection Kit
Specimen will be rejected if collected with Aptima Vaginal Swab Specimen Collection Kit.
Vaginal specimens:
Use Aptima Multitest swab specimen collection kit.
Specimen will be rejected if collected with Aptima Unisex swab specimen collection Kit.
Aptima Multitest swab specimen collection kit or
Aptima Unisex swab specimen collection kit
Urine specimens must be transferred to an Aptima specimen transport tube by the collecting site, within 24 hours of collection, and prior to specimen transport.
Swab:
Ambient (preferred) - 60 days
Refrigerated - 60 days
Frozen - NO
Urine:
Ambient (preferred) - 30 days
Refrigerated - 30 days
Frozen - NO
Target Capture with Transcription-Mediated Amplification
Negative
|
Neisseria gonorrhoeae probe versus patient infected status |
|
Specimen |
Sensitivity (%) |
Specificity (%) |
Female endocervical swab |
99.2 |
98.7 |
Female urine |
91.3 |
99.3 |
Female vaginal swab |
97.3 |
99.2 |
Male urethral swab |
99.1 |
97.8 |
Male urine |
98.5 |
99.6 |
Overall |
97.8 |
98.9 |