Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.
Immediatley following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
Spin within two (2) hours of sample collection
Lt green plasma separator (PST)
Immediately following collection, thoroughly mix sample by gently inverting 5 times
Gold serum separator (SST) tube
Architect:
Refrigerated (preferred) - 7 days
Frozen - 12 months
Roche:
Refrigerated (preferred) - 7 days
Ambient: 2 days
Frozen - 1 year
Architect:
Chemiluminescent Microparticle Immunoassay (CMIA)
Roche:
Electrochemiluminescence immunoassay (ECLIA)
Architect:
Age | Male | Female |
30 days | 25 - 200 ng/mL | 25 - 200 ng/mL |
3 months | 200 - 600 ng/mL | 200 - 600 ng/mL |
6 months | 50 - 200 ng/mL | 50 - 200 ng/mL |
15 years | 7 - 140 ng/mL | 7 - 140 ng/mL |
Adult | 22 - 275 ng/mL | 15 - 205 ng/mL |
Roche:
Male: 20 - 60 years |
30 - 400 ng/ml |
Female: 17 - 60 years |
15 - 150 ng/ml |