MYC by FISH [malignant tissue]

Alphabetical Test listing

MYC by FISH [malignant tissue]-4280J

  
MYC by FISH [malignant tissue]
  
4280J
  
LAB4280J - CYTOGENETICS MALIGNANT TISSUE STUDIES
  
CG MYC or MYC
  
Burkitt Lymphoma
Diffuse Large B-Cell Lymphoma
FISH
Fluorescence in Situ Hybridization
High Grade B-Cell Lymphoma
MYC
t(8;14)
t(2;8)
t(8;22)
8q24
  

To identify patients with MYC (chromosome 8q24) rearrangements including Burkitt lymphomas and to help differentiate diffuse large b-cell lymphoma from high grade lymphoma.

This test can be ordered individually or as part of a High Grade Lymphoma FISH Panel (See the panel test for details).

  
Malignant tumor tissue
  
5 mm (3)
  

Place a 5mm3 sample of involved tissue (solid tumor or other) in a sterile cup with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

 

  

Sterile cup with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

 

  
Formalin-fixed, paraffin embedded (FFPE) tissue block
Slides: 2 plus one H & E stained slide
  

Fix the tissue in 10% formalin and prepare a Formalin-fixed, paraffin embedded (FFPE) tissue block

Either the entire block,  or two (2) 5 micron cuts mounted on positively charged slides and one H&E stained slide can be submitted for testing

  

FFPE tissue block or

Tissue section mounted on a charged, unstained slide

  
  • AHL Cytogenetics oncology requisition
  

Ambient

  
FFPE specimens:
Slides - 6 months
Blocks - returned post reporting

Fresh tissue – until testing is reported.
  
  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Improper storage
  • Leaking container
  • Slides broken beyond repair
  
AHL - Cytogenetics: X
  
5 days
  

Fluorescence in situ hybridization (FISH)

  

Normal or Abnormal with interpretation

  
FFPE specimens:
88366x1 – Qualitative Morphometric FISH
This test includes a charge for application of the 2 FISH probes and professional interpretation of the results. If no cells are available for analysis, no analysis charges will be incurred

Fresh tissue specimens:
88271 x 2
88275
  
Yes
  
  
03/26/2021