Sex hormone-binding globulin

Alphabetical Test listing

Sex hormone-binding globulin-13363

  
Sex hormone-binding globulin
  
13363
  
LAB13363
  
SHG
  
SHBG
TeBG
Testosterone-binding globulin
  
  • This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R).
  • It is recommended to ask all patients who may be indicated for this test about biotin supplementation.
  • Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
  
Serum
  
  
1.0 mL
  
0.7 mL
Note: This volume does not allow for repeat testing
  

Spin

  

Gold serum separator (SST) tube

  
  

Spin and separate

  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

  
LabCorp Burlington (082016): R-LC
  
Mo - Sa
  
1 - 2 days
  

Electrochemiluminescence immunoassay (ECLIA)

  

Male
20-49 years: 16.5−55.9 nmol/L
>49 years: 19.3−76.4 nmol/L

Female
20-49 years: 24.6−122.0 nmol/L
>49 years: 17.3−125.0 nmol/L

  

Levels of SHBG are under the positive control of estrogens and thyroid hormones, and are suppressed by androgens. These influences dynamically control the liver synthesis of this carrier protein. Decreased levels of SHBG are frequently seen in hirsutism, virilization, obese postmenopausal women, and in women with diffuse hair loss. Increased levels may be present in cases of hyperthyroidism, testicular feminization, cirrhosis, male hypogonadism, pregnancy, women using oral contraceptives, and prepubertal children.

  
Biotin interference - see Patient preparation
  
84270
  
Result 13967-5
  
04/11/2019
  
08/13/2021
  
08/24/2021