Neuron-specific enolase, CSF

Alphabetical Test listing

Neuron-specific enolase, CSF-994

 

 

  
Neuron-specific enolase, CSF
  
994
  
LAB994
  
MSO
  
CJD
Creutzfeldt-Jakob disease
Neuron specific enolase CSF
NSE
  
  • An auxilliary test in the diagnosis of Creutzfeldt-Jakob disease
  • An auxilliary test in the diagnosis of small cell lung carcinoma metastasis to central nervous system or leptomeninges
  
Cerebral spinal fluid (CSF)
  

Sterile vial/container

  
0.5 mL
  
0.3 mL
  

Sterile vial/container

  

Refrigerated (preferred) - 15 days

Ambient - 72 hours

  
Mayo Clinic Laboratories (NSESF): R-MM
  
Mo - Sa
  
1 - 4 days
  

Homogeneous time-resolved fluorescence (HTRF)

  

Normal: ≤ 15 ng/mL

Indeterminate: 15-30 ng/mL  

Elevated: >30 ng/mL

Elevated results may indicate the need for additional workup. Possible causes may be NSE-secreting central nervous system/leptomeningeal tumor or rapid neuronal destruction from a variety of causes. In the context of dementia, elevated results may be suggestive of Creutzfeldt-Jakob disease.
 

  
83520
  
03/31/2004
  
10/16/2018
  
05/01/2020