Detect neutralizing antibodies to poliovirus (types 1 and 3). The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against the other type.
Immediately following collection, thoroughly mix sample by gently inverting 5 times
Gold serum separator (SST) tube
Refrigerated (preferred) - 2 weeks
Ambient – 48 hours
Frozen – 1 year
Semi-quantitative serum neutralization
< 1:10 |
No detectable poliovirus antibodies. |
≥ 1:10 |
Antibody to poliovirus detected, which may represent prior immunization or current or past infection. |