RUNX/RUNX1 by FISH

Alphabetical Test listing

RUNX/RUNX1 by FISH-4280H (blood) or 4280G (bone marrow)

  
RUNX/RUNX1 by FISH
  
4280H (blood) or 4280G (bone marrow)
  
LAB4280H - CYTOGENETIC LEUKEMIC BLOOD STUDIES
LAB4280G - CYTOGENETIC BONE MARROW STUDIES
  
RUNX/RUNX1
  
AML
Acute Myeloid Leukemia
FISH
Fluorescence in situ hybridization
t(8;21)
  

Detecting RUNX/RUNX1 or t(8;21), a recurring abnormality in AML.

This test can be ordered individually or as part of the AML FISH Panel. See the panel test for more details

  
Sodium heparin (Na hep) whole blood
  
  
5 mL
  
2.0 mL
  
  • Only one specimen tube is required to perform all ordered cytogenetics testing.
  • The more testing requested, the closer to the optimal volume requirements is required.
  

Dk green Sodium heparin (Na hep), no gel

  
Bone marrow
EDTA whole blood (a chromosome analysis study is not recommended for this specimen type)

  

EDTA whole blood (not recommended)

Lavender (EDTA), 4mL

  
Bone marrow: 10 mL (minimum 5 mL)
  

Bone marrow

Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube

  

- or -

Collect bone marrow in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel

  

Bone marrow:

Sterile vial/tube

Dk green Sodium heparin (Na hep), no gel

 

EDTA whole blood:

Lavender (EDTA), 4mL

  
  • AHL Cytogenetics oncology request
  

Ambient

  
Pellets - 2 years
  
  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Improper blood/anticoagulant ratio
  • Delay in transport
  • Improper storage
  • Leaking container
  
AHL - Cytogenetics: X
  
Mo, We, Fr
  
Routine: 5 - 7 days
STAT: Available upon request
  

Fluorescence in situ hybridization (FISH)

  

Normal or Abnormal with interpretation

t(8;21) RUNX/RUNX1 rearrangements are classified as favorable cytogenetics prognostic indicators in AML.

  
88271 x 2
88275
  
Yes
  
  
03/23/2021