Glypican-3 by IHC

Alphabetical Test listing

Glypican-3 by IHC-12376 - Technical only, 12379 - Technical & Interpretation

  
Glypican-3 by IHC
  
12376 - Technical only, 12379 - Technical & Interpretation
  
LAB12376
LAB12379
  
GPC3
  

All IHC stains will include a positive control tissue

  
Tissue
  

Submit a formalin-fixed, paraffin-embedded tissue

  

Formalin-fixed, paraffin-embedded (FFPE) tissue block

  

Tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • Glypicans are heparan sulfate proteoglycans (HSPGs) that are linked to the cell membrane by a glycosyl phosphatidylinositol (GPI) anchor
  • GPC3 is upregulated at mRNA and protein level in hepatocellular CA
  • Appears to be oncofetal (in fetal but not adult normal livers)
 

Staining pattern

  • Granular cytoplasmic and membranous staining

  

 

 

  
88342 - 1st stain
88341 - each additional stain
  
07/03/2017
  
10/18/2018
  
10/02/2020