11-Deoxycorticosterone, Serum

Alphabetical Test listing

11-Deoxycorticosterone, Serum-994

  
11-Deoxycorticosterone, Serum
  
994
  
LAB994
  
MSO
  
DOCS
DOC
11-deoxycorticosterone
Deoxycorticosterone
21-hydroxyprogesterone
Desoxycortone
INN
Deoxycortone
BAN
Cortexone
Substance Q
desoxy compound B
21-Hydroxy-4-pregnene-3,20-dione
  

Diagnosis of suspected 11-hydroxylase deficiency, including the differential diagnosis of 11 beta-hydroxylase 1 (CYP11B1) versus 11 beta-hydroxylase 2 (CYP11B2) deficiency

Diagnosis of glucocorticoid-responsive hyperaldosteronism

Evaluating congenital adrenal hyperplasia newborn screen-positive children, when elevations of 17-hydroxyprogesterone are only moderate, suggesting possible 11-hydroxylase deficiency

  

Morning (8 a.m.) specimen is preferred.

  
Serum
  

Red serum vial/tube - 5 mL

  
0.5 mL
  
0.4 mL
  

Immediately following collection, mix sample by gently inverting 5 times.

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Centrifuge within two (2) hours of collection
  3. Transfer the serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
  4. Refrigerate
  

Screw cap transfer vial/tube (Mayo T914)

  

Gold serum separator (SST) tube

  

Mix sample by gentle inversion, 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Refrigerated (preferred) – 21 days

Ambient - 7 days

Frozen - 21 days

  
14 days
  

Gross Hemolysis

  
Mayo Clinic Laboratories (DOCS): R-NX
  
Tuesdays
  
3 - 10 days
  

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

  

≤18 years: <30 ng/dL

>18 years: <10 ng/dL

  
82633
  
1656-8
  
02/08/2023
  
03/08/2023