Anti-cardiolipin antibodies belong to a heterogeneous family of anti-phospholipids. They are autoantibodies that are directed against anionic phospholipids or protein-phospholipid complexes. They are found in a wide range of conditions either transiently, in some infectious diseases, or more persistently in autoimmune diseases such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). Anti-cardiolipin antibodies have also been associated with a range of clinical conditions including: fetal loss, endocarditis, stroke, heart attack, and autoimmune hemolytic anemia.
The presence of cardiolipin antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in assessing the risk of thrombosis in individuals with System Lupus Erythematosus (SLE) or lupus-like disorders.
Gold serum separator (SST) tube
Spin and separate
Refrigerated (preferred) - 7 days
Ambient - NO
Chemiluminescent Immunoassay (CIA)