Cardiolipin antibody (IgA, IgM & IgG)

Alphabetical Test listing

Cardiolipin antibody (IgA, IgM & IgG)-661

  
Cardiolipin antibody (IgA, IgM & IgG)
  
661
  
LAB661
  
CRD
  
Phospholipid antibody
Anti-phospholipid antibody
anti-Cardiolipin antibody
  

Anti-cardiolipin antibodies belong to a heterogeneous family of anti-phospholipids. They are autoantibodies that are directed against anionic phospholipids or protein-phospholipid complexes. They are found in a wide range of conditions either transiently, in some infectious diseases, or more persistently in autoimmune diseases such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). Anti-cardiolipin antibodies have also been associated with a range of clinical conditions including: fetal loss, endocarditis, stroke, heart attack, and autoimmune hemolytic anemia.

The presence of cardiolipin antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in assessing the risk of thrombosis in individuals with System Lupus Erythematosus (SLE) or lupus-like disorders.

 

  
  • Assay results should be used in conjunction with clinical findings and other serological tests
  • This assay has not been validated to run in pediatric patients

 

 

 

  
Serum
  
  
1.0 mL
  
0.5 mL
  

Spin

  

Gold serum separator (SST) tube

  
  

Spin and separate

  
  

Refrigerated (preferred) - 7 days

Frozen (OK)

Ambient - NO

  
  • Improper labels (unlabeled or mislabeled)
  • Gross hemolysis 
  • Gross lipemia
  • Heparinized plasma
  • Contamination
  • Heat-treated sample
  • Contains visible particulates
  • Delay in transport
  • Improper storage temperature affecting results
  • Improper container
  • Leaking container resulting in compromised specimen
  • Quantity not sufficient (QNS)
  
AHL - Immunology: J
  
Tu, Th
  
2 - 3 days
  

Chemiluminescent Immunoassay (CIA)

  
Negative: < 20 CU
Positive:   ≥ 20 CU
  
86147 x 3
  
11/30/2001
  
09/07/2018
  
02/17/2020