CD7 by IHC

Alphabetical Test listing

CD7 by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
CD7 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  

All IHC stains will include a positive control tissue

  
  • CD7 is used in the evaluation of T-cell malignancies. It is the most frequently lost pan T cell marker in T-cell lymphomas
  • CD7 must be used in a panel with other T-cell markers
  
Tissue
  

Submit a formalin-fixed, paraffin-embedded tissue

  

Formalin-fixed, paraffin-embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • CD7 antibody is a pan T-cell marker that recognizes a human T cell and NK cell 40KD glycoprotein
  • CD7 antigen is an early expressed marker that persists throughout T cell differentiation
  • CD7 is found on the majority of peripheral T lymphocytes, most NK cells, and on thymocytes
  • CD7 expression can also be found in acute myeloid leukemias

Staining pattern

  • Cell surface membrane staining


References

  1. Reinhold U, et al: CD7 T-cells represent a subset of normal human blood lymphocytes. J Immunol 150(5);: 2081-2089, 1993.
  2. Picker LJ, et al: Immunophenotypic criteria for the diagnosis of non-Hodgkin's lymphoma. Am J Pathol 1987; 128:181-201.
  
88342 - 1st stain
88341 - each additional stain
  
05/15/2017
  
11/05/2018
  
10/02/2020