Human Immunodeficiency Virus 1 (HIV-1) PhenoSense Integrase

Alphabetical Test listing

Human Immunodeficiency Virus 1 (HIV-1) PhenoSense Integrase-994

  
Human Immunodeficiency Virus 1 (HIV-1) PhenoSense Integrase
  
994
  
LAB994
  
MSO
  
INSTI
Integrase strand inhibitor
Monogram Integrase Inhibitor Resistance
PhenoSense integrase
Raltegravir
  

The PhenoSense Integrase® assay is a phenotypic resistance test used to determine the susceptibility of a patient's HIV to integrase inhibitors. Integrase inhibitors block HIV replication by preventing the virus from integrating into the host cell's DNA. Raltegravir (Isentress®) is the first approved drug in this class of HIV antiretroviral drugs.

  
EDTA plasma
  
  
3.0 mL
  

Spin, separate and freeze immediately

Do not send specimens until they are completely frozen, as nucleic acid degradation occurs rapidly at ambient and higher temperatures.

Specimen integrity is compromised with freeze/thaw cycles.

 

  
  • Current viral load (≥ 500 copies/mL)
  

Frozen (strict)

  
Monogram Biosciences (S3200) via LabCorp (550230): R-NX
  
Varies
  
19 - 23 days
  

Reverse Transcription-Polymerase Chain Reaction (RT-PCR)

  

See report

  
87903
  
06/05/2013
  
01/21/2020