IgA by IHC

Alphabetical Test listing

IgA by IHC-12376 - Technical only, 12379 - Technical & interpretation

IgA by IHC
12376 - Technical only, 12379 - Technical & interpretation
Immunoglobulin A
  • All IHC stains will include a positive control tissue
  • IgA labels plasma cells and related lymphoid cells containing IgA
  • IgA stains will show an interstitial dendritic pattern within lymphoid follicles, (this represents extracellular immune complexes which are bound to the surface of specialized follicular dendritic cells)
  • IgA will label occasional B cell lymphomas

Submit a formalin-fixed, paraffin-embedded tissue


Formalin-fixed, paraffin-embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • This antibody reacts with heavy chains (alpha) of human IgA (Fc-part)
  • This antibody labels plasma cells and various lymphocytes

Staining pattern

  • Cytoplasmic (plasma cells) and cell surface membrane (lymphocytes)


  1. Taylor CR et al: The demonstration of plasma cells and other immunoglobulin-containing cells in formalin-fixed, paraffin-embedded tissues using peroxidase-labelled antibody. J Clin Pathol 1974; 27:14-20.
  2. Taylor CR et al: The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique. Clin exp Immunol 1974; 8:417-29.
88342 - 1st stain
88341 - each additional stain