Mephenytoin

Alphabetical Test listing

Mephenytoin-1997

Test name:

Mephenytoin

Test number:

1997

Excellian order number:

82492.11

Abbreviation:

Mephenytoin

Alternate names:

MEP
Mesantoin
Nirvanol

Useful for:

Therapeutic drug management

Specimen type:

Serum

Collection container:

Red serum vial/tube, 5 mL

Volume:

2.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Trough levels are most reproducible

Processing instructions:

Allow sample to clot
Spin
Transfer serum to a TSerum/plasma transfer vial/tube (MedTox), labelled as serum, within two (2) hours of sample collection

Transport container:

Serum/plasma transfer vial/tube (MedTox)

Alternate specimen type:

Heparin plasma

Alternate collection container:

Dk green heparin (Li or Na), no gel

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting

Alternate processing instructions:

Spin
Transfer plasma to a Serum/plasma transfer vial/tube (MedTox), labelled as the appropriate plasma type, within two (2) hours of sample collection

Transport and stability:

Refrigerated (preferred)

Ambient - 3 days

Frozen (OK)

Performing lab:

MedTox Laboratories (68): R-MX

Days set up:

Varies

TAT:

4 days

Method:

High Performance Liquid Chromatography with Ultraviolet Detection; (HPLC-UV)

Reference ranges:

Mephenytoin: 1.0 - 5.0 µg/mL

Normephenytoin (Nirvanol): 15.0 - 35.0 µg/mL

Results that require action (critical):

Mephenytoin
High: 20 µg/mL

Normephenytoin (Nirvanol)
High: 50.0 µg/mL

CPT codes:

G0480

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

11/30/2001

Revised date:

10/15/2020

Review date:

01/04/2024