CSF3R mutation analysis

Alphabetical Test listing

CSF3R mutation analysis-994

  
CSF3R mutation analysis
  
994
  
LAB994
  
MSO
  
Colony stimulating factor 3 receptor
CSF3R
  
Bi-directional sequencing of exons 14 and 17 of the CSF3R gene which includes detection of the common mutation T618I (also known as T595I).
  

CSF3R mutations are newly-identified genetic markers detected in 59% of chronic neutrophilic leukemia (CNL) or atypical chronic myeloid leukemia (aCML) that are useful for diagnosis and classification of these disorders. Identification of specific mutations may suggest the class of kinase inhibitors to which the tumor will be sensitive. Mutations are also detected in 30-80% of leukemia in patients with severe congenital neutropenia (SCN).

  
EDTA whole blood
  
  
4 mL
  

Mix by gentle inversion, 8 - 10 times.

  

Lavender (EDTA), 4mL

 

  
Bone marrow
  
2 mL
  

Place 2 mL of bone marrow into a Lavender (EDTA), 4mL tube.

Mix by gentle inversion, 8 - 10 times.

  

Refrigerated (preferred)

Ambient -

Frozen -

  
  • Improper label (unlabeled or mislabeled)
  • Clotted specimen
  • Improper anticoagulant or ratio
  • Improper storage/transport temperature
  
Neogenomics: R- NX
  
Varies
  
12 days
  

Molecular

  
81479
  
Yes
  
  
10/18/2021
  
10/18/2021