Alpha-1 antitrypsin

Alphabetical Test listing

Alpha-1 antitrypsin-14275

  
Alpha-1 antitrypsin
  
14275
  
LAB14275
  
A1A
  
Acute Phase Proteins
Alpha1-Protease Inhibitor
  

Detection of hereditary decreases in the production of α1-antitrypsin (α1AT). Decreased or nearly absent levels of α1AT can be a factor in chronic obstructive lung disease and liver disease. An increased prevalence of non-MM phenotypes is found with cryptogenic cirrhosis and with CAH. Cirrhosis in a child should raise consideration of α1AT deficiency or Wilson's disease. Diagnosis of inflammatory states, if elevated (eg, rheumatoid arthritis, bacterial infection, vasculitis, neoplasia).

  

Overnight fasting prior to sample collection is preferred

Fasting for a blood test

  
Serum
  
  
1.0 mL
  
0.3
Volume does not allow for repeat testing
  

Spin

  

Gold serum separator (SST) tube

  
EDTA plasma
Heparin plasma
  

Red/lavender - spin and separate

Lt Green PST - spin

  

Red/lavender:

Transfer vial/tube with cap - 12mL (LabCorp)

Lt green plasma separator (PST)

 

 

  

Ambient (preferred)

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

  
  • Chylous serum
  
LabCorp Burlington (001982): R-LC
  
Mo - Fr, Su
  
1 - 2 days
  

Immunologic

  

See report

  
82103
  
04/21/2020
  
07/10/2020