Cytochrome P450 2C19 genotyping

Alphabetical Test listing

Cytochrome P450 2C19 genotyping-13653

  
Cytochrome P450 2C19 genotyping
  
13653
  
LAB13653
  
CYTOP450C19
  
Cytochrome P450 2C19
CYTOP4502C19
GeneSight
PGx
Pharmacogenomics
Pharmacogenetics
  

This testing can assist with customizing drug therapy by providing metabolic activity information that may explain patient drug responses relevant to CYP2C19 genetic variability. The cytochrome P450 (CYP450) enzymes metabolize many drugs. Individual genetic differences of cytochrome P450 activity can result in the total absence of metabolism to ultrafast metabolism of certain drugs.

  
EDTA whole blood
  
  
5.0 mL
  
3.0 mL
  

Lavender (EDTA), 10mL

  
ACD whole blood
  

Yellow ACD (A or B)

 

 

  

Yellow ACD (A or B)

  

Molecular Medicare billing request

  • Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
  • All information requested is required in order for your request to be completed
  

Ambient (preferred) - 7 days

Refrigerated - 7 days

Frozen - 2 years

  
  • Hemolysis
  • Quantity not sufficient for analysis
  • Improper container
  
Esoterix Coagulation (301552) via LabCorp (511675): R-LC
  
Once per week, or as needed
  
5 - 10 days
  

DNA analysis of the Cytochrome P450 2C19 gene (OMIM 124020, 10q24.1-10q24.3) is performed using primer extension chemistry. Multiplex PCR amplifies DNA fragments containing the variants below. Primer extension then generates a biotin-labeled product to perform flow-sorted detection of both normal and variant sequences. Molecular-based testing is highly accurate, but as in any laboratory test, rare diagnostic errors may occur. Alleles Detected: *1,*2,*3,*17 *1 represents detection of the normal sequence for the variant sites tested.

  

An interpretive report will be provided

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection
  
81225
  
Yes
  
  
Result 57132-3
  
04/23/2019
  
12/21/2020
  
02/19/2021