4Kscore kit test

Alphabetical Test listing

4Kscore kit test-994

Test name:

4Kscore kit test

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

4K score
4K prostate screen
Kallikrein score
Four K

Useful for:

The 4Kscore Test calculates your risk for aggressive prostate cancer by measuring several proteins in the blood and combining that with clinical findings.

It can be used after an abnormal PSA result if you are considering a prostate biopsy.

Limitations:

***For order by Allina Health providers only***

4Kscore Test is not indicated for men if:

Previous diagnosis of prostate cancer
Younger than 45 years of age
Within 96 hours after a digital rectal examination
Receiving 5-alpha reductase inhibitors (5ARIs) therapy within the previous 6 months
Undergone any significant, invasive urological procedure or therapy that may be associated with secondary PSA elevation within the prior 6 months

Specimen type:

Serum

Collection container:

Speckled top Serum separator tube (SST) X 2 (collection tubes provided in kit).

Kit/specialty tubes must be requested from the Central lab supply prior to patient arriving in the lab

Volume:

4 mL

Collection instructions:

Patient should arrive with completed 4Kscore test requisition.
Time sensitive: Specimens should be collected Monday – Thursday. Specimens must be received at the Central lab by 1pm.
Immediately following collection, mix sample thoroughly by gentle inversion, 5 times
Send specimens and completed paperwork to the Central Lab

Processing instructions:

Allow sample to clot.
Centrifuge for 10 minutes.

Transport container:

Original collection tubes

Required forms/information:

4Kscore test requisition- to be completed by the provider and signed by the patient

Transport and stability:

Refrigerated - 72 hours

**SPECIMEN MUST BE SHIPPED WITHIN 24HRS OF COLLECTION**

Performing lab:

BioReference Laboratories (J148-8) : R-NX

Days set up:

Mo- Fr

TAT:

3 days

Method:

Electrochemiluminescence Immunoassay

Reference ranges:

Interpretive report will be provided

Clinical information:

The 4Kscore test result is the probability of finding high-grade, aggressive prostate cancer (Gleason 7 or higher) if a prostate biopsy were to be performed.

A 4Kscore <5.0 is associated with decreased likelihood of a Gleason score ≥7 on biopsy. Prostate biopsy is required for the diagnosis of cancer. The test is not recommended more than once every 6 months.

Date created:

07/20/2022

Revised date:

10/20/2023

Review date:

10/20/2023