BG-8 by IHC

Alphabetical Test listing

BG-8 by IHC-12376 - Technical only, 12379 - Technical & interpretation

BG-8 by IHC
12376 - Technical only, 12379 - Technical & interpretation
Blood group 8
  • All IHC stains will include a positive control tissue
  • Useful in identifying cells of epithelial origin
  • Reacts with 92-100% of lung adenocarcinomas (strong, diffuse cytoplasmic staining)
  • Mesotheliomas (8-23%) will also stain, but the reactivity is weak and usually limited to a few cells
  • Patients with Lewis Y antigen on their blood cells will also show positive staining in the RBC's

Submit a formalin-fixed, paraffin embedded tissue block


Formalin-fixed, paraffin embedded (FFPE) tissue block


Tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • BG-8 is a monoclonal antibody raised against a lung cancer cell line that also recognizes the blood group antigen Lewis Y

Staining patterns

  • Cytoplasmic staining


  1. Ordonez NG. The immunohistochemical diagnosis of epithelial mesothelioma. Hum Pathol 1999; 30: 313-23.
  2. Riera JR, et al: The immunohistochemical diagnostic panel for epithelial mesothelioma. A reevaluation after heat-induced epitope retrieval. Am J Surg Pathol 21:1409-1419, 1997.
  3. Jordon D. et al: Blood group antigens Lewis X and Lewis Y, in the diagnostic discrimination of malignant mesothelioma versus adenocarcinoma. Am J Pathol 135:931-937, 1989.


88342 - 1st stain
88341 - each additional stain