Neuromyelitis Optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, spinal fluid

Alphabetical Test listing

Neuromyelitis Optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, spinal fluid-12780

  
Neuromyelitis Optica (NMO)/Aquaporin-4-IgG fluorescence-activated cell sorting (FACS) assay, spinal fluid
  
12780
  
LAB12780
  
NMOFC
  
AQP
AQP4
Aquaporin
Devic's Antibody
NMO (Neuromyelitis Optica)
NMO-IgG
NMO/AQ
Optic Neuritis Ab
Transverse Myelitis Antibody
Vision Loss Antibody
  
  • Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
  • Diagnosis of autoimmune AQP4 channelopathy
  • Distinguishing NMOSD from multiple sclerosis early in the course of disease
  
Cerebrospinal fluid (CSF)
  
3.0 mL
  
2.0 mL
  

Sterile vial

  

Refrigerated (preferred) - 28 days

Frozen - 28 days

Ambient - 72 hours

  
28 days
  
Mayo Clinic Laboratories (NMOFC): R-MM
  
Mo, Tu, Th
  
3 - 6 days
  

Flow Cytometry

  

Negative

  
A negative result does not exclude a diagnosis of neuromyelitis optica spectrum disorder (NMOSD). Recommend serum be tested if CSF tests negative and neuromyelitis optica spectrum disorder is suspected. AQP4-IgG antibodies may drop below detectable levels
  
86255
86256-NMO/AQP4-IgG FACS titer (if appropriate)
  
08/19/2015
  
12/04/2020
  
06/02/2020