Viscosity, serum

Alphabetical Test listing

Viscosity, serum-13331

  
Viscosity, serum
  
13331
  
LAB13331
  
VISCOSITY
  
Serum viscosity
  

Evaluate hyperviscosity syndrome associated with monoclonal gammopathy states (myeloma, macroglobulinemia of Waldenstrom, and other dysproteinemias), including occasional cases of rheumatoid arthritis, SLE, systemic lupus erythematosus, hyperfibrinogenemia.

Hyperviscosity most frequent (33% of cases) with IgM monoclonal gammopathy (Waldenstrom macroglobulinemia); next with IgA myeloma. When IgG myeloma leads to hyperviscosity, IgG levels are usually very significantly elevated. A relative viscosity of 6-7 usually results in symptoms of the hyperviscosity syndrome, they have however been described with lower levels of relative viscosity (ie, 4).] Neonatal hyperviscosity, usually but not always associated with polycythemia, may be accompanied by a fairly typical clinical picture. Plethora, hypoglycemia, lethargy, and jitteriness/seizures (CNS symptoms) occur. There may be symptoms and findings suggesting congenital heart disease (CHD) (ie, respiratory distress, cardiacenlargement, and cyanosis). False diagnoses of CHD have been made in such cases. About 50% of such infants have modest hyperbilirubinemia (bilirubin >12 mg/dL).

  
Serum
  
  
1.0 mL
  
0.5 mL
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Refrigerated (preferred)  - 14 days

Ambient - 14 days

Frozen - 14 days

Freeze/thaw cycles: stable x3

  
  • Hemolysis
  • Fibrin clots
  • Quantity not sufficient for analysis
  
LabCorp Burlington (004861): R-LC
  
Mo - Fr
  
2 - 5 days
  

Viscometry

  

0 - 5 years:   not established

6 - 50 years: 1.4 - 2.0

>50 years:    1.4 - 2.1

  
85810
  
Result 3128-6
  
04/11/2019
  
03/16/2021
  
03/16/2021