Fluconazole, serum or plasma

Alphabetical Test listing

Fluconazole, serum or plasma-994

  
Fluconazole, serum or plasma
  
994
  
LAB994
  
MSO
  
Diflucan
  

Treatment of candidiasis, cryptococcal meningitis, and antifungal prophylaxis in allogeneic bone marrow transplant recipients.

  
Serum
  
  
1.0 mL
  
0.5 mL
  

Spin and separate

  
EDTA plasma
  
  

Spin and separate

  

Transfer vial/tube with cap - 12mL (LabCorp)

  

Refrigerated (preferred) - 14 days

Ambient - 14 days

Frozen - 14 days

  
  • Serum from gel-barrier tubes is not acceptable and will be rejected
  
LabCorp Burlington (700485): R-NX
  
Mo - Fr
  
3 - 7 days
  

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

  
The average peak concentration in fasted patients one to two hours after administration of a single oral 400mg dose of Fluconazole was 6.72 µg/mL (range 4.12 - 8.08).
 
No relationship between plasma concentrations and efficacy or toxicity has been identified for Fluconazole, however, exposure may be altered in instances of renal dysfunction or renal replacement therapy.
  
80299
  
Result 10987-6
  
10/09/2019
  
10/14/2019
  
07/22/2020