Toxoplasma gondii by IHC

Alphabetical Test listing

Toxoplasma gondii by IHC-12376 - Technical only, 12379 - Technical & interpretation

Toxoplasma gondii by IHC
12376 - Technical only, 12379 - Technical & interpretation
  • All IHC stains will include a positive control tissue
  • In paraffin tissue, the antibody specifically and quantitatively labels toxo trophozoites
  • Identification of toxo is especially important in the immunocompromised host
  • Identification of toxo in the placenta correlates with congenital toxoplasmosis and can be associated with mental retardation and blindness



Submit a formalin-fixed, paraffin embedded tissue block


Formalin-fixed, paraffin embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • Toxoplasma is a sporozoan that lives as intracellular parasites in various tissues and organs of vertebrate animals and completes its life cycle in a single host
  • This protozoan can be transmitted via undercooked meat, contaminated soil, or by direct contact
  • The antibody is specific for toxo, and can identify the trophozoites in the bloodstream, in tissue, and in reticuloendothelial cells, leukocytes and in epithelial cells

 Staining pattern

  • Membranous


  1. Conley et al: Toxoplasma gondii infection of the central nervous system. Use of the PAP method to demonstrate Toxoplasma in formalin-fixed, paraffin-embedded tissue sections. Hum Pathol 12:690-698, 1981.
88342 - 1st stain
88341 - each additional stain