Investigation of suspected red cell membrane disorders such as hereditary spherocytosis or hereditary pyropoikilocytosis
Submit a patient specimen, control specimen and 2 well-made peripheral blood smears (Wright stained or fixed in absolute methanol).
Allina facility special instructions:
Refrigerate specimens immediately; do not spin.
Rubber band patient specimen and control vial together.
Lavender (EDTA), 4mL
Refrigerated - 72 hours
HSEV: Consultative interpretation
FRAGO: Osmotic lysis
BND3: Flow cytometry
SMPB: Consultant review
≥ 12 months:
0.50 g/dL NaCl (unincubated): 3-53% hemolysis
0.60 g/dL NaCl (incubated): 14-74% hemolysis
0.65 g/dL NaCl (incubated): 4-40% hemolysis
0.75 g/dL NaCl (incubated): 1-11% hemolysis
An interpretive report will be provided.