Mycobacterium tuberculosis Rifampin PCR

Alphabetical Test listing

Mycobacterium tuberculosis Rifampin PCR-12932

  
Mycobacterium tuberculosis Rifampin PCR
  
12932
  
LAB12932
  
MTR
  
MTB PCR
MTB/RIF PCR
TB
TB PCR
  

An MTB/RIF PCR result of “not detected”, from either one or two sputum specimens, is highly predictive of the absence of M. tuberculosis bacilli on fluorescent acid-fast sputum smears from patients with suspected active pulmonary tuberculosis, and can be used as an aid in the decision of whether continued airborne infection isolation is warranted.

  
Sputum
  
  
  • Induced or expectorated sputum
  • First morning sputa yield best results
  

Screw cap plastic container (sterile)

  

Induced sputum container

  

Induced sputum container

  

Refrigerated (preferred) - 10 days

Ambient - 3 days

  
  • Improper label (unlabeled or mislabeled)
  • Time delay between time of collection and receipt of specimen
  • Improper transport container
  • Improper transport temperature
  • Interfering substances
  • Inappropriate specimen type
  • Leaking container
  
AHL - Microbiology: M
  
Daily
  
1 day
  

Real Time polymerase chain reaction (RT-PCR)

  

Not detected

  

The MTB/RIF PCR Assay is not indicated for use with sputum samples from patients being treated with antituberculosis drugs, either to determine bacteriologic cure, or to monitor response of the therapy.

A negative test does not exclude the possibility of isolating MTB-complex from the sputum sample. The MTB/RIF PCR assay must be used in conjunction with mycobacterial culture to address the risk of false negative results, and to recover the organism for further characterization and susceptibility testing.

A positive test does not necessarily indicate the presence of viable organisms.

MTB positive samples will detect and report the presence or absence of mutations associated with Rifampin resistance (at an additional charge)

  • Test must be ordered in conjunction with an AFB culture & smear (6617/LAB6617)
  • Test may also be ordered as an add-on to an AFB culture & smear up to 7 days after collection of the sample
  
87556

Additional CPT code (if appropriate):
87798
  
02/13/2019
  
02/19/2019
  
03/04/2020