Mast cell tryptase by IHC

Alphabetical Test listing

Mast cell tryptase by IHC-12376 - Technical only, 12379 - Technical & Interpretation

  
Mast cell tryptase by IHC
  
12376 - Technical only, 12379 - Technical & Interpretation
  
LAB12376
LAB12379
  
MCT
  
  • In paraffin tissue, the antibody labels mast cells and is most useful in identifying mast cell related diseases
  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications:

  • The antibody reacts with human mast cell tryptase, isolated from human lung tissues
  • Tryptase is a protease found in the granules of mast cells, and is a mediator of inflammation
  • Anti-mast cell tryptase labels mast cells in many tissues including respiratory and GI tracts, skin, conjunctiva and brain
  • This antibody does not label basophils

Staining pattern:

  • Cytoplasmic granular staining

References

  1. Walls et al: Immunohistochemical identification of mast cells in formaldehyde-fixed tissue using monoclonal antibodies specific for tryptase. J Pathol 1990;162:199-126.
  
88342 - 1st stain
88341 - each additional stain
  
07/17/2017
  
10/19/2018
  
10/02/2020