Mast cell tryptase by IHC

Alphabetical Test listing

Mast cell tryptase by IHC-12376 - Technical only, 12379 - Technical & Interpretation

Mast cell tryptase by IHC
12376 - Technical only, 12379 - Technical & Interpretation
  • In paraffin tissue, the antibody labels mast cells and is most useful in identifying mast cell related diseases

Submit a formalin-fixed, paraffin embedded tissue


Formalin-fixed, paraffin embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • The antibody reacts with human mast cell tryptase, isolated from human lung tissues
  • Tryptase is a protease found in the granules of mast cells, and is a mediator of inflammation
  • Anti-mast cell tryptase labels mast cells in many tissues including respiratory and GI tracts, skin, conjunctiva and brain
  • This antibody does not label basophils

Staining pattern:

  • Cytoplasmic granular staining


  1. Walls et al: Immunohistochemical identification of mast cells in formaldehyde-fixed tissue using monoclonal antibodies specific for tryptase. J Pathol 1990;162:199-126.
88342 - 1st stain
88341 - each additional stain