BCL6 by FISH
BCL6 by FISH-4280G
Diffuse large B-cell lymphoma
FISH
Fluorescence in situ hybridization
High grade B-cell lymphoma
Large B-cell lymphoma
3q27
BCL6 rearrangements are associated with Large B-cell lymphoma and can help differentiate diffuse Large B-cell lymphoma from High-grade lymphoma.
This test can be ordered individually or as part of a High Grade B-cell Lymphoma FISH Panel. See the panel test for details.
Bone marrow aspirate:
Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube
- or -
- Collect bone marrow in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel
- Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting
Transfer aspirate from syringe to transport container.
Submit entire specimen unspun.
Touch Prep Slides
Bone Marrow core:
Submit in sterile tube/cup filled with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline
Submit entire specimen.
Sterile tube/cup
AHL Cytogenetics Oncology Request
Ambient
- Improper label (unlabeled or mislabeled)
- Wrong container (anticoagulant or solution)
- Delay in transport
- Improper storage
- Leaking container
- Slides broken beyond repair
Fluorescence in situ hybridization (FISH)
Normal or Abnormal with interpretation