Therapeutic drug management
Spin and separate serum or plasma from the red cells within two hours of sample collection
Ambient (preferred) - 3 days
For storage beyond three days, specimen should be refrigerated or frozen.
Gas chromatography/flame ionization detection (GC/FID)
Therapeutic and toxic ranges have not been established
Usual therapeutic doses produce mitotane serum concentrations of less than 100 µg/mL