The F2-isoprostane/creatinine is the 'gold standard' for measuring oxidative stress and has utility in individuals who have lifestyle risks due to poor diet or smoking, a family history of cardiovascular disease, or hyperlipidemia. High levels are seen in conditions associated with increased risk of atherosclerosis and certain cancers.
Screw cap plastic container (sterile)
Frozen (preferred) - 6 months
Refrigerated - 7 days
Ambient - 48 hours
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)