Bile acids, fractionated and total, LC/MS-MS

Alphabetical Test listing

Bile acids, fractionated and total, LC/MS-MS-994

  
Bile acids, fractionated and total, LC/MS-MS
  
994
  
LAB994
  
MSO
  

This assay uses LC/MS-MS to quantify the free acid, glycine-conjugate and taurine-conjugate forms of cholic acid, chenodeoxycholic acid, deoxycholic acid, and ursodeoxycholic acid. Bile acids may be measured to investigate obstructive cholestasis in pregnancy. In addition, bile acids are required for cholesterol absorption, fat-soluble vitamin absorption, and to provide resistance to overgrowth of intestinal bacteria. Bile acid levels may be reduced or elevated due to various genetic defects.

  
Serum
  
  
1.0 mL
  
0.3 mL
Submitting the minimum volume does not allow for repeat testing
  

Spin within two hours of specimen collection

 

  

Gold serum separator (SST) tube

  
EDTA plasma
Sodium heparin (Na Hep) plasma
  

Spin and separate within two (2) hours of collection

  
  

Refrigerated (preferred) - 3 days

Ambient - 1 days

Frozen - 14 days

  
  • Whole blood
  
Esoterix Endocrinology (803640) via LabCorp (503640): R-NX
  
Tu, Th, Sa
  
3 - 5 days
  

High-pressure liquid chromatography/tandem mass spectrometry (HPLC/MS-MS)

  

Ursodeoxycholic acids

  < 1.9

Cholic acids

 < 2.2

Chenodeoxycholic acids

  < 5.8

Deoxycholic acids

  < 3.3

Total Bile acids

  < 9.2

  

Bile acids may be measured to investigate obstructive cholestasis in pregnancy. In addition, bile acids are required for cholesterol absorption, fat-soluble vitamin absorption, and to provide resistance to overgrowth of intestinal bacteria. Bile acid levels may be reduced or elevated due to various genetic defects.

  
82542
  
Result:
503641 Total Bile Acids 14628-2
503642 Ursodeoxycholic Acids 55159-8
503643 Cholic Acids 30518-5
503644 Chenodeoxycholic Acids 30519-3
503645 Deoxycholic Acids 30520-1
  
05/31/2019
  
02/02/2021
  
05/19/2020