Antichromatin antibodies

Alphabetical Test listing

Antichromatin antibodies-994

Antichromatin antibodies
Antibodies to LE cell

Help to diagnose drug-induced lupus (DIL) and systemic lupus erythematosus (SLE).

Antibodies to both chromatin and histones have been found in patients with procainamide-induced lupus; however, patients with lupus induced by drugs such as quinidine, penicillamine, methyldopa, and acebutolol have antibodies to chromatin but not antihistone. Antichromatin antibodies are found in 50% to 90% of SLE patients and have been linked with proteinuria in SLE patients.

1.0 mL
0.5 mL
Submission of the minimum volume does not allow for repeat testing

Immediatley following collection, mix sample by gently inverting 5 times

  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection

Gold serum separator (SST) tube

  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

  • Hemolysis
LabCorp Burlington (012580): R-NX
Mo - Sa
4 days

Multiplex flow immunoassay


0.0 - 0.9 AI

Result 51775-5