Antiglomerular basement membrane antibodies

Alphabetical Test listing

Antiglomerular basement membrane antibodies-13364

  
Antiglomerular basement membrane antibodies
  
13364
  
LAB13364
  
GBM
  
Anti-GBM
Antiglomerular BM Ab
Glomerulonephritis
Goodpasture pulmo-renal syndrome
Goodpasture syndrome
  

Anti-GBM antibodies (glomerular basal membrane; Goodpasture antigen) are important for the diagnosis of glomerulonephritis, which may be accompanied by pulmonary hemorrhage (Goodpasture pulmo-renal syndrome). Due to clinical symptoms similar with systemic vasculitis, it is appropriate to concurrently carry out tests for anti-GBM and Antineutrophil cytoplasmic antibodies (ANCA).

  
Serum
  
  
0.6 mL
  
0.3 mL
  

Immediatley following collection, mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

  
  • Microbially contaminated, heat-treated specimens or specimens containing visible particulate
  • Grossly hemolyzed specimen
  • Grossly lipemic specimen
  
LabCorp (163050): R-LC
  
5 days
  

Multiplex flow immunoassay

  

Negative;  <1.0 units/mL

  

This test is often used in conjunction with the antineutrophil cytoplasmic antibody (ANCA) test for Wegener granulomatosis and vasculitis.

  
83516
  
03/27/2019
  
06/27/2022
  
06/27/2022