Lamotrigine

Alphabetical Test listing

Lamotrigine-8452

  
Lamotrigine
  
8452
  
LAB8452
  
LMX
  
Lamictal
  
Serum
  
  
2.0 mL
  
0.5 mL
  

A steady state, trough (pre-dose) sample is generally accepted as most consistent for therapeutic drug monitoring of Lamotrigine.

  

Spin and separate

  

Refrigerated - 7 days

Frozen - 1 month

  
AHL - Chemisty: C
  
Daily; Can be ordered STAT
  
Routine - 1 day;STAT - 2 hours
  

Competitive Immunoassay

  

Therapeutic: 3.0 - 15.0 µg/mL

  

The target steady state trough range for seizure control is 3.0 - 15.0 µg/mL.

Concentrations that exceed 15 µg/mL may contribute to adverse effects. Patient response varies widely, particularly with co-medications and/or compromised renal function.

  
80175
  
11/15/2010
  
10/02/2018