An adjunct to β2-glycoprotein and anticardiolipins in diagnosing aPS (antiphospholipid syndrome) for assessing thrombotic risk and other obstetric complications such as miscarriage or fetal growth restriction.
Immediatley following collection, mix sample by gently inverting 5 times
Gold serum separator (SST) tube
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
Enzyme-linked immunosorbent assay (ELISA)
IgM: 0 - 30 MPS
IgA: 0 - 19 APS
IgG: 0 - 30 GPS
High serum levels of antiphospholipid antibodies are frequently detected in patients with autoimmune (ie, SLE) and nonautoimmune diseases, as well as in apparently healthy individuals. These antibodies have been associated with an increased risk for recurrent arterial and venous thrombotic events, thrombocytopenia, and fetal loss.