6q21 by FISH
6q21 by FISH-4280H (blood) or 4280G (bone marrow)
LAB4280G - CYTOGENETIC BONE MARROW STUDIES
CLL full panel
Chronic Lymphocytic Leukemia
SLL
Small Lymphocytic lymphoma
6q21
6q21 Deletion
Deletion of 6q21 is a common abnormality in a variety of B-cell disorders including Acute B-Cell Lymphocytic Leukemia (CLL)/ Small Lymphocytic lymphoma (SLL).
This test can be ordered individually or as part of a CLL full panel (see the individual panel test for more details).
- Only one specimen tube is required to perform all ordered cytogenetics testing.
- The more testing ordered, the closer to the optimal volume requirements is preferred.
- Immediatley following collection, mix sample by inverting 5 - 10 times to prevent clotting
Dk green Sodium heparin (Na hep), no gel
EDTA whole blood (a chromosome analysis study is not recommended for this specimen type)
Bone marrow
Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube
- or -
Collect bone marrow in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel
EDTA whole blood:
Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting
EDTA whole blood:
Lavender (EDTA), 4mL
Bone marrow:
Sterile vial/tube
Dk green Sodium heparin (Na hep), no gel
- AHL Cytogenetics oncology requisition
Ambient
- Improper label (unlabeled or mislabeled)
- Wrong container (anticoagulant or solution)
- Improper blood/anticoagulant ratio
- Delay in transport
- Improper storage
- Leaking container
Fluorescence in situ hybridization (FISH)
Normal or Abnormal with interpretation