Heparin antibodies, polyspecific

Alphabetical Test listing

Heparin antibodies, polyspecific-8775

  
Heparin antibodies, polyspecific
  
8775
  
LAB8775
  
PHA
  
HIT
HAT
Heparin induced platelet antibody
  

This is a screening assay to aid in determining the risk for heparin induced thrombocytopenia (HIT).

  
Sodium citrate (Na cit) plasma
  

Lt blue Sodium citrate (Na Cit) - 2.7mL

If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.

Hematocrit-Anticoagulant adjustments

  
1.5 mL
  
  • Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical

Coag – tube fill guidelines

  • Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting
  
  
  

Frozen (strict)

Refrigerated - NO

  
  • Specimen collected in Greiner tube(s)
  • Improper labeling (unlabeled or mislabeled)
  • Improper anticoagulant
  • Improperly filled tube
  • Hemolysis
  • Clotted specimen
  • Delay in transport
  • Improper storage/transport temperature
  • Patient on heparin > 1.0 IU/mL
  
AHL - Coagulation/Special Coagulation: V
  
Daily: 11am
  
1 - 2 days
Same day if received by 10:30am
  

Immunoturbidimetry

  

Negative

  

This is a screening assay. Results should be used in conjunction with other laboratory and clinical findings to aid in determining the risk for heparin induced thrombocytopenia (HIT). A negative result of testing for human platelet factor 4 (H/PF4) antibodies has about a 90% negative predictive value. Positive results may indicate the presence of heparin-associated antibodies but a positive result does not confirm the diagnosis of HIT. The serotonin release assay (SRA) remains the gold-standard test for confirmatory HIT diagnosis due to its high sensitivity and specificity.

  
86022
  
05/04/2011
  
03/19/2024
  
01/12/2024