D-Dimer, quantitative
D-Dimer, quantitative-3433
Fibrin degradation products
XDP
The D-Dimer is a terminal product in the degradation of fibrin. The D-Dimer is proof that the fibrinolytic system is responding to some coagulation activation.
Increased levels of the D-Dimer are seen in:
- DIC
- Thromboses: Deep vein thrombosis (DVT) or in Pulmonary Emboli (PE). The D-Dimer can be used as a negative predictor value to rule out these conditions.
- Other activation of coagulation system: Cancers, post-operative stage, cirrhosis, hemorrhages.
Lt blue Sodium citrate (Na Cit) - 2.7mL
If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.
- Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical
- Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times to prevent clotting
- Process Platelet Poor Plasma (P.P.P)
- Transfer plasma into an aliquot tube using a spot label "NaCit Plasma P.P.P" to label as platelet poor plasma
- Freeze immediately
Microcentrifuge vial/tube in a Snap cap conical vial/tube and cap (Beaker sites)
Coagulation specimen transport vial/tube (all other sites)
Send whole blood sample in original collection container with STAT courier.
Must be tested within 4 hours of collection.
Lt blue Sodium citrate (NaCit) - 2.7mL
Plasma:
Frozen (strict)
Refrigerated - NO
Whole blood:
Ambient - 4 hours
Refrigerated - NO
- Improper label (unlabeled or mislabeled)
- Improper anticoagulant
- Improperly filled tube
- Hemolysis
- Clotted specimen
- Delay in transport/exceeds standard testing time
- Improper storage/transport temperature
- Unlabled specimen
- Patient on heparin > 1.0 IU/mL
- Specimens collected in Grenier tubesPlasma samples that are not completely frozen
Immuno-turbidimetric
< 0.5 µg/mL