Anti thrombin lll activity
Anti thrombin lll activity-621
ATIII
Since the first report of a hereditary deficiency of AT III and its consequences in 1965, AT III has been considered an important parameter in spontaneous thromboembolic disorders. The hereditary deficiency, either quantitative or qualitative, is less common than the acquired deficiency. An acquired AT III deficiency has been described in DIC, septic shock, nephrotic syndrome, liver disease and in L-asparaginase treatments.
Two (2) Lt blue Sodium citrate (Na Cit) - 2.7mL tubes
If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.
- Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical
- Immediatley following collection, mix sample by gentle inversion 3 - 4 times to prevent clotting
-
Process Platelet Poor Plasma (P.P.P)
Coag – how to prepare a specimen for special coagulation testing
- Transfer plasma into an aliquot tube using a spot label "NaCit Plasma P.P.P" to label as platelet poor plasma
- Freeze immediately
Microcentrifuge vial/tube in a Snap cap conical vial/tube and cap (Beaker sites)
Coagulation specimen transport vial/tube (all other sites)
Frozen (strict) - 2 weeks
Refrigerated - NO
- Improper label (unlabeled or mislabeled)
- Improper anticoagulant
- Improperly filled tube
- Hemolysis
- Clotted specimen
- Delay in transport
- Improper storage/transport temperature
- Patients on heparin >1.0 IU/mL
- Plasma samples not completely frozen
Available STAT
Chromogenic
| Age | Range in % |
|---|---|
| 0 - 5 days | 40-95 |
| 6 - 30 days | 48-108 |
| 1 – 6 mo | 70-125 |
| >7 mo | 80-135 |