Protime/INR

Alphabetical Test listing

Protime/INR-487

  
Protime/INR
  
487
  
85610.0
  
PT
  
PT
Prothrombin time
  
  • A basic coagulation screening test for the assessment of congenital and acquired deficiencies of the extrinsic pathway (factors II, V, VII, X).
    • The Prothrombin time can be prolonged in certain clinical states, i.e. warfarin therapy, intestinal reabsorption disorders, liver failure, fibrinolysis and DIC
  • To monitor warfarin therapy
  
Sodium citrate (Na cit) whole blood
  

 Lt blue Sodium citrate (Na Cit) - 2.7mL 

If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.

Hematocrit-Anticoagulant adjustments

  
2.7mL
  
  • Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical

Coag – tube fill guidelines

  • If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube. Refer to the Collection container for instructions.
  • Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting
  

Test must be run within 24 hours of collection.

  

Lt blue Sodium citrate (Na Cit) - 2.7mL tube

  
Sodium citrate (Na cit) plasma
  

If the sample will not reach the AHL Central Laboratory within 24 hours:

  1. Process Platelet Poor Plasma (P.P.P)

    Coag – how to prepare a specimen for special coagulation testing

  2. Transfer plasma into an aliquot tube using a spot label "NaCit Plasma P.P.P" to label as platelet poor plasma
  3. Freeze immediately
  
  

Whole blood:

Ambient - 24 hrs

Plasma:

Frozen (OK)

  
  • Greiner tubes are not acceptable
  • Improper labeling (unlabeled or mislabeled)
  • Improper anticoagulant
  • Improperly filled tube
  • Hemolysis
  • Clotted specimen
  • Delay in transport
  • Improper storage/transport temperature
  
AHL - Coagulation: W
  
Daily
  
1 day
  

Clot Based Assay

  

Protime: 10.6 - 12.4 seconds

INR:

  Age Range 
  0-2 months 0.53-1.3
  3-6 months 0.6-1.2
  Adult ≤1.2
Therapeutic (most patients)   2.0-3.0
Therapeutic (high risk patients)   2.5-3.5

 

  

0 - 28 days: > 1.3

>28 days:    > 6.0

  
85610
  
Yes
  
  
11/30/2001
  
10/15/2024
  
01/12/2024