Thrombin time

Alphabetical Test listing

Thrombin time-510

  
Thrombin time
  
510
  
85670.2
  
TT
  
TT
  
Sodium citrate (Na cit) plasma
  

Lt blue Sodium citrate (Na Cit) - 2.7mL 

If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.

Hematocrit-Anticoagulant adjustments

  
1.5 mL
  
0.6 mL
  
  • Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical

Coag – tube fill guidelines

  • Mix by gentle inversion 3 - 4 times
  
  • Process Platelet Poor Plasma (P.P.P)
  1. Coag – how to prepare a specimen for special coagulation testing

 

  

Microcentrifuge vial/tube in a Snap cap conical vial/tube and cap (Beaker sites)

     

   

Coagulation specimen transport vial/tube  (all other sites)

                  

 

 

  

STAT requests only:

Send whole blood sample in original collection container with STAT courier.

Must be tested within 4 hours of collection.

  

Lt blue Sodium citrate (Na Cit) - 2.7mL 

  

Routine:

Frozen (strict)

Refrigerated - NO

Ambient - NO

Stat:

Ambient - 4 hours

  
  • Samples collected in Greiner tubes
  • Improper anticoagulant
  • Improperly (over or under) filled tube
  • Hemolysis
  • Patient on heparin > 1.0 IU/mL
  • Exceeds standard testing time
  • Incorrectly labeled or mislabeled
  • Clotted specimen
  • Plasma samples not completely frozen
  
AHL - Coagulation: W
  
Daily
  
1 day
  

Clot based assay

  

<17 sec

  

Prolongation of the thrombin time indicates:

  • An abnormality of fibrinogen
    • Qualitative; dysfibrinogenemia
    • Quantitative congenital: hypofibrinogenemia or afibrinogenemia
    • Quantitative acquired: DIC, fibrinolysis, liver disease
  • The presence of antithrombins
    • Therapeutic: heparin, hirudin, argatroban
  
85670
  
11/30/2001
  
05/18/2021
  
02/18/2020