D-Dimer, quantitative

Alphabetical Test listing

D-Dimer, quantitative-3433

D-Dimer, quantitative
Fibrin degradation products

The D-Dimer is a terminal product in the degradation of fibrin. The D-Dimer is proof that the fibrinolytic system is responding to some coagulation activation.

Increased levels of the D-Dimer are seen in:

  • DIC
  • Thromboses: Deep vein thrombosis (DVT) or in Pulmonary Emboli (PE). The D-Dimer can be used as a negative predictor value to rule out these conditions.
  • Other activation of coagulation system: Cancers, post-operative stage, cirrhosis, hemorrhages.


Sodium citrate (Na cit) plasma

Lt blue Sodium citrate (Na Cit) - 2.7mL

If the patient has a hematocrit >55, a specially prepared Lt blue Sodium citrate (NaCit) tube must be used in place of the standard Lt blue Sodium citrate (NaCit) tube.

Hematocrit-Anticoagulant adjustments

2.0 mL
  • Do not over or under fill tube as the ratio of anticoagulant to whole blood is critical

Coag – tube fill guidelines

  • Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times to prevent clotting
Sodium citrate (Na cit) whole blood - STAT requests only

Send whole blood sample in original collection container with STAT courier.

Must be tested within 4 hours of collection.


Lt blue Sodium citrate (NaCit) - 2.7mL



Frozen (strict)

Refrigerated - NO


Whole blood:

Ambient - 4 hours

Refrigerated - NO

  • Improper label (unlabeled or mislabeled)
  • Improper anticoagulant
  • Improperly filled tube
  • Hemolysis
  • Clotted specimen
  • Delay in transport/exceeds standard testing time
  • Improper storage/transport temperature
  • Unlabled specimen
  • Patient on heparin > 1.0 IU/mL
  • Specimens collected in Grenier tubesPlasma samples that are not completely frozen
AHL - Coagulation: W
1 day



< 0.5 µg/mL